Home » Resources » PCRI Papers

PCRI Papers

The sections below contain papers meant to inform you on the various aspects of prostate cancer. Most of the papers were originally published in the PCRI Insights newsletter. Many have been converted to Web pages with key terms linked to the PCRI Glossary. Some sections include references to additional articles that have been published in Insights with a PDF link to an image of the article (or issue). You can download these articles in Adobe Acrobat (PDF) format by using the links provided. If you would like to receive a printed copy of the issue, contact the PCRI Helpline.

Some of these Papers contain opinions of the authors based on their clinical practice or research at the time of the article and may not reflect their current thinking. Information provided in these papers should not be taken as medical advice and should be discussed with a patient's physicians.

 

Index to all PCRI Papers

Basics

     Nutrition

• Diet, Vitamins & Exercise for Prostate Cancer PCRI Pamphlet 2010
• Herbal, All Natural – Are they safe? Are they effective? PDF Stanley Brosman, MD 2010
• Update On Omega 3 and Prostate Cancer – Mark Moyad, MD, MPH 2011 PDF
• Integrative Medicine and Prostate Cancer: A Look at the Currently Available Evidence PDF Geo Espinosa, ND 2009
• Can Natural Dietary Supplements Really Impact Prostate Cancer? • Jacek Pinski, MD, PhD 2007
• Advances in Holistic PC Chemoprevention and Treatment • Aaron Katz, M.D. 2008
• Food For Thought: Pomegranate Juice and Tomato Products Show Promise PDF Mark Dreher, Ph.D. 2009
• Pomegranates and Prostate Health: A Research Report • Mark Dreher, Ph.D. 2008
• The Linkage Between Obesity and Prostate Cancer • David Heber, MD, PhD, FACP, FACN 2004
• Some Basic Facts on PC (Testing and Nutrition) 2001
• Can Diet Really Control Prostate Cancer? • Mark Scholz, MD and Ralph Blum 2006
• Nutritional Recommendations for Active Prostate Cancer • Stephen B. Strum, MD 1999
• General Comments on Diet 1996
  

 

Undiagnosed

     Pre-Clinical Phase

• Screening for Prostate Cancer PCRI Pamphlet 2010
• The PCRI Views Regarding Testing for Prostate Cancer 2004
• What Every Doctor Who Treats Male Patients Should Know • Stephen B. Strum, MD, FACP and Donna Pogliano 2005
• Using PSA Intelligently to Manage Prostate Cancer, Part 1 • Jonathan McDermed, PharmD 2003
  • Part 2 2005
• What Do We Know About PSA Screening Now That It's 2009? PDF
• For Your Sons PDF • Jan Manarite 2009
• Chemoprevention of Prostate Cancer PDF • Paul Schellhammer, MD 2010
• PCA3: A Genetic Marker of Prostate Cancer • Alejandra B.Torres and Leonard S.Marks, MD 2006
• PSA Doubling Time 2009 (update)
• Prostatic Intraepithelial Neoplasia PIN 1998
• Prostate Disorders Other Than Cancer – Part 2 BPH PDF • Stanley Brosman, MD 2010
• Prostate Disorders Other Than Cancer – Part 1 Prostatitis PDF • Stanley Brosman, MD 2010
• Eleven Decisions Before Prostate Biopsy PDF 2011
• Infection Associated With Prostate Biopsies 1 - Paul Schellhammer, MD 2011 PDF

 

Newly Diagnosed

     Self-Empowerment

• Newly-Diagnosed - the Very Basics • Mark Scholz, MD and Richard Lam, MD 2008
• Finding the Best Treatment • Mark Scholz, MD 2004
• E-Empowerment • Arthur Lurvey, MD 2004
• Levels of Evidence PDF 2009
• A Medical Miranda for the PC Patient 1998
• What We Should Have Learned about PC in the Last 10 Years. - Stephen B. Strum, MD, FACP 2008
  • Part 1 – Prostate Cancer Landscape and the Potential for Prevention
  • Part 2 – Exploring the Lessons from the Prostate Cancer Prevention Trial
  • Part 3 – The Use the PSA and Derivative Tools in Diagnosis and Staging
• The PCRI Glossary: A Tool for Learning About PC
• Who's At Risk for What? • Mark Scholz, MD 2005
  • Laboratory Tests Defined
• Participating in a Prostate Cancer Clinical Trial • Stanley A. Brosman, MD 2005

     Risk Assessment and Algorithms

• A Strategy Of Success in the Treatment of Prostate Cancer • Stephen B. Strum MD 2002
• Newly Diagnosed PC: Evaluating the Options (Part 1 - Introduction) • Mark Scholz, MD 2003
• Risk Assessment for Prostate Cancer PDF • Matthew R. Cooperberg, MD, MPH 2010
• Partin Tables for Predicting Extent of Disease 2009 (updated)
• Prostate Cancer Algorithms/Nomograms  2011 (updated)
• Creating Your PC Digest - v1.1, PDF 1998
  

     Staging

• The Clinical Stage: Its Definition and Importance in Prostate Cancer • Harry Pinchot and Stephen B. Strum MD 2000
• Understanding Your Biopsy Results 1998
• Targeted Biopsies and Active Surveillance PDF • David B. Agus, MD 2010
• The Gleason Score: Prostate Cancer Aggressiveness On Biopsy • Gerry J. O’Dowd et al 2001
• Gleason Grade Migration: Changes in Prostate Cancer Grade in the Contemporary Era • Daniel J. Luthringer, MD and Mitchell Gross, MD 2006
• The Great Prostate Cancer Stage Migration PDF 2009
• Should a Second Opinion be Obtained When a Biopsy is Positive? PDF • Stanley Brosman, MD 2010
• Does Finasteride Alter the Pathology of the Prostate and Cancer Grading? • David G. Bostwick MD 2004
• Ploidy Analysis 2000

     Diagnostic Scanning

• Color Doppler and Tissue Harmonic Ultrasound • Duke Bahn, MD 2002
• Magnetic Resonance Anatomic and Spectroscopic Imaging of Prostate Cancer – Current Status • John Kurhanewicz, Christopher K. Sotto and Fergus Coakley 2006
• Endorectal MRI with spectroscopy - 2000 • UCSF Prostate Cancer MRI/MRSI Group
• MRI for Prostate Cancer PDF • Daniel J A Margolis, MD 2010
• MRI in Prostate Cancer • Jelle Barentsz, M.D., Ph.D 2008
• Update on ProstaScint: CT and MRI Fusion as Diagnostic Tools • Samuel Kipper, MD 2003
• Ferumoxtran-10 (Combidex): An Important New Prostate Cancer Staging Tool • Maha Torabi, MD and Mukesh G. Harisinghani, MD 2004
• Bone Scan 2000

 

Local Therapies

     Treatment for Localized Disease

• How to Pick the Best Treatment for Prostate Cancer PCRI Pamphlet 2010
• Newly Diagnosed PC: Evaluating the Options (Part 2 - for lower risk patients) • Mark Scholz, MD 2003
  1. Deferred therapy (previously known as watchful waiting)
  2. Androgen deprivation therapy (ADT)
  3. Brachytherapy (Seeds)
  4. Surgery (radical prostatectomy)
  5. Intensity modulated radiation therapy (IMRT)
  6. Cryotherapy (Cryo)
  7. High Dose Radiation (HDR) Monotherapy
• Which PC Therapy Has the Best Long Term PSA Control? PDF
• Active Surveillance For Favorable Risk Prostate Cancer:
  What Are The Results, and How Safe Is It? - Laurence Klotz, MD et al. 2006
• Active Surveillance with High Resolution Color-Doppler Transrectal Ultrasound Monitoring • Duke Bahn, MD, Mark Scholz, MD, and Richard Lam, MD 2007
• Treatment Choices for Early (Localized) Prostate Cancer PDF • Grace Lu-Yao, PhD & Siu-Long Yao, MC 2010
• Radical Prostatectomy • Stanley Brosman, MD 2003
• Long Term Results of Surgery for Localized PC PDF • Stanley Brosman, MD 2010
• Nerve Sparing Robotic Prostatectomy • Ashutosh Tewari, MD, Mani Menon, MD, et al 2004
• Nerve Sparing Robotic Prostatectomy -Update • Ashutosh Tewari, MD 2007
• Prostate Seed Implantation for Prostate Cancer • Peter Grimm, DO, et al. 2003
• High Dose Rate (HDR) Brachytherapy • D. Jeffrey Demanes MD, FACRO, FACR 2007
• Temporary Seed Implant with High Dose Rate Brachytherapy (HDR) • Glenn Gejerman, MD 2003
• Salvage High Dose Rate Brachytherapy After Radiation • Paul Y. Song, M.D. 2008
• Update On Image-Guided Radiation Therapy PDF • Patrick Kupelian, MD 2011
• Intensity Modulated Radiation Therapy (IMRT) • Lisa Chaiken, MD, et al. 2004
• Nine Decisions Before Choosing Radiation Therapy After Prostatectomy PDF 2010
• Cryoablation of the Prostate • Duke K. Bahn, MD, et al. 2005 
• Salvage Options for Rising PSA After Primary Therapy – Nathan Roundy 2011 PDF
• Salvage Brachytherapy – Paul Song, MD 2011 PDF
• Salvage Cryotherapy – Duke Bahn, MD PDF

     Novel Therapies

• Has the Time Come for Focal Therapy of Prostate Cancer? • Martin J Weissman, M.D. 2008
• Review of Focal Therapy for Localized Prostate Cancer PDF 2010
• Transrectal High Intensity Focused Ultrasound: The Next Generation? • HIFU • Douglas O. Chinn, MD 2005
• HIFU Treatment Outcome Data Is Maturing PDF 2011
• CancerCryo-Immunotherapy: A Battle Between the Immune System and Cancer • Haakon Ragde, MD and Duke K. Bahn, MD 2006

 

Systemic Therapies

• Newly Diagnosed PC: Evaluating the Options (Part 3 - for higher risk patients) • Mark Scholz, MD 2004

     Androgen Deprivation Therapy

• Testosterone Inactivating Pharmaceuticals • Mark Scholz, MD 2010
• Testosterone Inactivating Pharmaceuticals PDF • Mark Scholz, MD & Ralph Blum 2010
• Beating Prostate Cancer with Hormonal Therapy • Charles Myers, MD 2007
• Adjuvant Androgen Withdrawal • Glenn Tisman, MD 2003
• Preventing Side Effects from Testosterone Inactivating Pharmaceuticals – Mark Scholz, MD 2010
• Preventing and Treating the Side Effects of Testosterone Deprivation Therapy - Brad Guess PA-C 2006
• Anti-androgen Monotherapy • Mark Scholz, MD 2010
• Avodart and Proscar • Mark Scholz, MD 2010
• Immune Treatment for PSA-Relapsed Prostate Cancer • Mark Scholz, MD 2010
• Bisphosphonates for Osteoporosis or Bone Metastasis • Mark Scholz, MD 2010
• Intermittent Androgen Deprivation • Stephen B. Strum, MD 2000
• Importance of Concordance in PC Management 2000
  

     Secondary Hormonal Therapy and Androgen Resistance

• Anti-androgen Withdrawal Response (AAWR)
  
• High Dose Ketoconazole Plus Hydrocortisone (HDK+ HC) 2004
  
• Androgen Resistance (Part 1) • Charles Myers, MD 2002
• Androgen Resistance (Part 2) 2003
• Androgen Resistance (Part 3) 2003

 

Androgen Independent PC

• Empowerment In Advanced & Hormone Refractory PC PDF • Jan Manarite 2009
• Listening to the Biology of PC • Stephen Strum, MD 2001
• Hormone-Refractory Prostate Cancer: A Continuum of Diseases and Options • Oliver Sartor, MD 2005
• Chemotherapy in Prostate Cancer • Richard Lam, MD 2009
• Chemotherapy for Prostate Cancer: "Why Bother?" • Brad Guess, PA-C 2006
• Dealing with Taxotere Side Effects • Richard Lam, MD 2007
• Important Principles in Chemotherapy (AIPC) • Stephen Strum, MD 1999
• Cytoxan 1997
• Logothetis Protocol 1998
• How do you Treat PC that has Progressed on Primary ADT?: Part 1 1998
• How do you Treat PC that has Progressed on Primary ADT?: Part 2
• PROVENGE® Approved in the U.S.A. PDF • Jan Manarite 2010
• New FDA Approval for Cabazitaxel (Jevtana®) PDF • Oliver Sartor, MD 2010

 

High Risk Prostate Cancer

• Bone -Targeted Therapy for Advanced Prostate Cancer • Oliver Sartor, MD 2009
• Newer Concepts in the Treatment of Hormone-Refractory Prostate Cancer with Bone Metastases • Oliver Sartor, MD 2005
• Bagley Regimen • Stephen B. Strum, MD 1998
• Servadio regimen of DES + Cytoxan + 5FU - 1998 v1.1, PDF
  
• Small Cell PC 1994
• Bone integrity relation to PC activity: extent of disease vs survival - 1999 v2.2, PDF

Novel Therapies

• Genetic Theories
• Immunotherapy And Advanced Prostate Cancer - By William Cavanagh 2008
• The Abscopal Effect - Using Cancer Against Itself - By William Cavanagh 2009
• Introduction to Monoclonal Antibodies 1996
• Dendritic Cells - Key to PC Immunotherapy • Frank Valone, MD - 2001 v4.4, PDF
• Update on Provenge Trials - Sept 2005
• Update on Provenge Trials - Nov 2006
• Cabozantinib (XL184) Phase II PDF • Mark Scholz, MD 2011

 

Treatment Side Effects

• Preventing and Treating the Side Effects of Testosterone Deprivation Therapy - Brad Guess PA-C 2006
• Side Effects of Androgen Deprivation Therapy Induced by Estrogen Deficiency - Neal Shore, MD& Stephen Freedland, MD 2009
• Dealing with Taxotere Side Effects - Richard Lam, MD 2007
• Anemia of Androgen Deprivation 1999
• Androgen Deprivation Syndrome (ADS) • Stephen B. Strum, MD 1999
• The Treatment of Erectile Dysfunction • Stephen M.Auerbach, MD 2005
• Incontinence Treatment Options for Post-Prostatectomy • Gary E. Leach, MD 2004
• Stenting of the Urethra for the Treatment of Urinary Complications Related to the Prostate PDF 2009
• Important Principles in Chemotherapy (AIPC) • Stephen Strum, MD 1999
• Photoselective Vaporization Prostatectomy: A Palliative Treatment Option for Men with Urinary Obstruction Secondary to Prostate Cancer • Mahmood A. Hai MD, FACS 2005
• Radiation Cystitis - Stanley Brosman, MD 2011 PDF

     Bone Integrity

• Bisphosphonates for Osteoporosis or Bone Metastasis • Mark Scholz, MD 2010
  
• Bone Integrity - in depth review • Stephen Strum, MD 1999
• Association between bone formation and destruction - 1999 v2.2, PDF
  

 

 

If you do not already have Adobe Reader® installed, Click here to get your free copy!